In this article, I will discuss the best cross-chain wallets with Ledger support. These wallets offer enhanced security, seamless multi-chain support, and compatibility with hardware wallets like Ledger, ensuring safe and easy management of digital assets across different blockchains.
Whether you’re into DeFi, NFTs, or general crypto storage, these wallets provide the versatility and protection you need.
Key Points & Best Cross-Chain Wallets With Ledger Support List
Wallet | Key Features |
---|---|
Hana Wallet | Cross-chain swaps, dApps access, staking |
DeFi Wallet | DeFi staking, yield farming, dApp integration |
MyEtherWallet (MEW) | Hardware wallet support, NFT management, swaps |
Zerion Wallet | DeFi portfolio tracking, swaps, NFT support |
MetaMask | Web3 dApp access, token swaps, multi-network support |
Guarda Wallet | Non-custodial, staking, multi-asset storage |
MyEOSWallet | EOS staking, governance, resource management |
Firefly Wallet | MIOTA token storage, feeless transactions |
Neon Wallet | NEO & GAS management, staking, dApps support |
9 Best Cross-Chain Wallets With Ledger Support
1.Hana Wallet
Hana wallet, known as a multichain wallet, supports the ICON, Ethereum and offers seamless cross-chain transactions allowing hassle-free management of multiple assets across networks in on place. It enhances security by providing Ledger support with private keys kept offline.
Users can take advantage of staking assets, dApps interaction alongside executing swaps. The sophisticated interface makes it possible for both novice and experienced blockchain users to enjoy.

ICON ecosystem participants prefer Hana Wallet due to its direct integration with the network’s governance and staking mechanisms. For blockchain enthusiasts, its powerful security features mixed with multichain capabilities makes it a top choice.
Feature | Details |
---|---|
Blockchain Support | ICON, Ethereum, and other EVM-compatible chains |
Ledger Support | Yes |
Security | Non-custodial, hardware wallet integration, private key control |
Key Features | Cross-chain swaps, staking, dApp access |
Best For | ICON ecosystem users, multi-chain asset management |
User Interface | Simple and intuitive |
Availability | Web extension and mobile |
2.DeFi Wallet
DeFi wallet is a non custodial versatile wallet meant for decentralized finance. It works with multiple blockchains such as Ethereum, Binance Smart Chain, etc. For advanced security taregets, Ledger integration is provided assuring secure transactions and asset management.

Defi developers and investors who actively participate in cryptocurrency staking and working with protocols such as Uniswap and Aave, will make use of built-in token swaps and yield farming features as passive income services. With its user-friendly interface, supportive for both novice and expert traders, DeFi wallet users no longer have to depend on centralized exchanges.
Feature | Details |
---|---|
Blockchain Support | Ethereum, Binance Smart Chain, Polygon, and other major networks |
Ledger Support | Yes |
Security | Non-custodial, private key control, hardware wallet integration |
Key Features | Staking, yield farming, token swaps, DeFi dApp access |
Best For | DeFi investors, yield farmers, and multi-chain users |
User Interface | Simple and user-friendly |
Availability | Mobile and desktop |
3.My Ether Wallet (MEW)
MyEtherWallet, also known as MEW, is one of the Ethereum wallets that comes highly recommended because of its robust security features, as well as putting users in control of their private keys. Those who possess a Ledger hardware wallet capable of storing ETH and ERC-20 tokens can do so and also manage them comfortably.
MEW directly connects the users with the Ethereum ecosystem, which includes dApps, DeFi projects, and NFTs. Token swapping, ETH staking, and using decentralized exchanges (DEXs) are other features that the users can take advantage of easily.

The open source nature of MEW makes it the preferred option for Ethereum enthusiasts as it guarantees security and transparency. MEW also increases the efficiency of gasless transactions while retaining decentralization and security, making it compatible with Ethereum layer two networks and other blockchain networks.
Feature | Details |
---|---|
Blockchain Support | Ethereum & EVM-compatible chains |
Ledger Support | Yes |
Security | Non-custodial, private key control, hardware wallet integration |
Key Features | ETH & ERC-20 token management, swaps, staking, dApp access |
Best For | Ethereum users, DeFi participants, NFT collectors |
User Interface | Intuitive and easy to navigate |
Availability | Web and mobile |
4.Zerion Wallet
Zerion Wallet is a multi-tasking DeFi wallet designed for managing portfolios and interaction with the blockchain. Advanced functions of the wallet also include supporting other Ethereum-based networks, Layer 2 networks giving users the ability to undertake transactions at lower fees.
Advanced DeFi features can be accessed with greater security when assets are stored in the wallet due to support for Ledger. Zerion serves active traders best as it provides instant and smooth token swaps, yield farming, and portfolio tracking in real-time.

Users can use the wallet through its intuitive interface to integrate dApps, allowing active lending, borrowing, and investing in crypto assets. Out of all the DeFi and NFT wallets, Zerion Wallet is the one that excels in performance because of possesing smart analytics alongside a streamlined experience.
Feature | Details |
---|---|
Blockchain Support | Ethereum, Layer 2s (Arbitrum, Optimism), Binance Smart Chain, Polygon |
Ledger Support | Yes |
Security | Non-custodial, private key control, hardware wallet integration |
Key Features | DeFi portfolio tracking, token swaps, staking, NFT management |
Best For | DeFi traders, NFT investors, multi-chain asset management |
User Interface | Clean and intuitive |
Availability | Mobile and web |
5.Meta Mask
MetaMask is regarded as one of the best and most used wallets for Ethereum and EVM. It offers incredible Web 3 features. Utilizing Ledger hardware wallets, MetaMask strengthens security while providing users with access to decentralized applications (dApps), DeFi platforms, and NFT marketplaces. Users can effortlessly switch between Ethereum, Binance Smart Chain, Polygon, and several other networks.

Its interface includes automatic token swaps and is easy to use for both novices and proficient people. With its browser extension and mobile app, MetaMask is still the primary wallet for the decentralized web. Its open-source architecture together with reliable updates makes it ideal for users of cryptocurrency.
Feature | Details |
---|---|
Blockchain Support | Ethereum, Binance Smart Chain, Polygon, Avalanche, and other EVM chains |
Ledger Support | Yes |
Security | Non-custodial, private key control, hardware wallet integration |
Key Features | Web3 dApp access, token swaps, multi-chain support |
Best For | DeFi users, NFT traders, Web3 enthusiasts |
User Interface | User-friendly, browser extension & mobile app |
Availability | Browser extension, mobile app (iOS & Android) |
6.Guarda Wallet
Guarda Wallet is a secure, self-custodial and multi-asset wallet for Bitcoin, Ethereum, Binance Coin and other cryptocurrencies. With Ledger integration, Guarda guarantees high-level security regarding private key storage. Users can stake a variety of assets, instantly swap tokens, and engage with DeFi applications.

The wallet is available on desktop, mobile, and web which allow seamless access across devices. Guarda’s user interface combined with extensive support of blockchains, make it a great option for people with diverse crypto portfolios. Users can also make cryptocurrency purchases using fiat, which aids in transitioning to the digital asset world.
Feature | Details |
---|---|
Blockchain Support | Bitcoin, Ethereum, Binance Smart Chain, Polygon, and 50+ blockchains |
Ledger Support | Yes |
Security | Non-custodial, private key control, hardware wallet integration |
Key Features | Multi-asset storage, staking, token swaps, built-in exchange |
Best For | Users managing multiple assets securely |
User Interface | Intuitive and easy to use |
Availability | Web, desktop, mobile, and browser extension |
7.MyEOSWallet
MyEOSWallet is a high-quality wallet for the EOS blockchain with enhanced security features through Ledger support.
It supports full control over EOS accounts enabling users to stake their tokens, vote on block producers, and handle resources in the best possible manner. Wallet facilitates effortless and quick transactions. MyEOSWallet is an all-encompassing and light wallet.

It is non custodial, thus users own their private keys. As EOS specialized wallet, it provides convenient access governance, supports dApps, and thus, serves the EOS community.
Feature | Details |
---|---|
Blockchain Support | EOS |
Ledger Support | Yes |
Security | Non-custodial, private key control, hardware wallet integration |
Key Features | EOS token management, staking, governance voting, resource management |
Best For | EOS users managing tokens and participating in governance |
User Interface | Simple and efficient |
Availability | Desktop and mobile |
8.Firefly Wallet
Firefly Wallet is a proprietary IOTA network wallet which enables secure and feeless transactions. Firefly also has Ledger support which allows users to store MIOTA safely while taking advantage of IOTA’s innovative Tangle technologies.
The wallet lets users send and receive funds instantly, interact with IOTA, and manage digital identities. With the combination of great user interface, robust security, and user data privacy, anyone on the network is well protected.

Additional smart contract support and staking features are expected in future updates. As IOTA grows, Firefly Wallet remain as the best option for the market willing to manage IOTA in a secured manner.
Feature | Details |
---|---|
Blockchain Support | IOTA |
Ledger Support | Yes |
Security | Non-custodial, private key control, hardware wallet integration |
Key Features | MIOTA token storage, feeless transactions, digital identity management |
Best For | IOTA users and ecosystem participants |
User Interface | User-friendly and clean |
Availability | Desktop and mobile |
9.Neon Wallet
Neon Wallet is a opensource wallet made for the NEO blockchain. It has Ledger hardware wallet support. This crypto wallet facilitates users to send, receive, or store GAS and NEO tokens while participating in governance activities; users can also earn GAS by stakng in the wallet.
Additionally, The Neon Wallet enables dApp integration, making it easier to interact with the peripherals of NEO’s network.

Interacting with all users is made easy with its powerful yet simple interface. Neon Wallet has established itself as a well-trusted lightweight and secure wallet for NEO blockchain users and continues to be the go-to for effortless user experience.
Feature | Details |
---|---|
Blockchain Support | NEO |
Ledger Support | Yes |
Security | Non-custodial, private key control, hardware wallet integration |
Key Features | NEO & GAS management, staking, dApp support |
Best For | NEO blockchain users |
User Interface | Simple and efficient |
Availability | Desktop and mobile |
Conclusion
To sum up, the most effective cross-chain wallets that integrate with Ledger ensure advanced security, smooth multi-chain asset management, and easy access to decentralized applications. Users, for example, of meta mask
Guarda, and Hana wallets, are non-custodial, meaning they have complete control of their private keys. These wallets provide solutions for secure and flexible crypto management whether it’s DeFi investments or NFTs.